Recent research highlights that female cancer survivors are disproportionately affected by cancer-related fatigue and depression compared to their male counterparts, leading to significant impacts on their quality of life and daily activities.
Higher Incidence in Women
A study presented at the American Association for Cancer Research (AACR) Annual Meeting 2025 analyzed data from 1,555 cancer survivors. The findings revealed that female survivors were 69% more likely to experience cancer-related fatigue and 58% more likely to suffer from depression than male survivors.
Impact on Daily Activities
Cancer-related fatigue and depression significantly reduce physical activity levels among survivors. Those experiencing fatigue were 86% more likely to decrease moderate recreational activities, such as brisk walking or gardening. Similarly, individuals with depression were 65% more likely to reduce both moderate and vigorous activities .
Underlying Factors
Several factors contribute to the heightened vulnerability of women to these conditions:
- Biological Differences: Women may experience more severe side effects from treatments like chemotherapy and radiation due to differences in drug metabolism and immune responses.([AACR][1])
- Hormonal Influences: Hormonal fluctuations can affect mood and energy levels, potentially exacerbating fatigue and depression.
- Social Roles: Women often bear greater caregiving responsibilities, which can increase stress and limit time for self-care, contributing to emotional and physical exhaustion.
Addressing the Disparity
Recognizing these gender-specific challenges is crucial for developing effective interventions. Healthcare providers should consider tailored strategies that address the unique needs of female cancer survivors, including
- Personalized Treatment Plans: Adjusting therapies to minimize side effects and manage symptoms effectively.
- Mental Health Support: Providing access to counseling and support groups to address depression and emotional well-being.
- Lifestyle Interventions: Encouraging physical activity and stress-reduction techniques to combat fatigue.
By acknowledging and addressing these disparities, healthcare systems can improve the overall well-being and recovery outcomes for female cancer survivors.
(DISCLAIMER: The views expressed are solely of the research basis. InDiagnostic shall not be responsible for any damage caused to any person/organisation directly or indirectly).
