Cancer-Related Fatigue and Depression Affect Women More Severely Than Men

Recent research states that people survived by female cancer are affected by fatigue and depression compared to their male counterparts, which has significant impact on their quality of life and daily activities. 

Higher Incidence in Women  

An annual meeting of the American Association for Cancer Research (AACR) An analysis of 1,555 cancers of cancer was analyzed in a study in 2025. Conclusions showed that women survivors were likely to experience cancer -related fatigue more than 69% more and were likely to suffer from 58% more depression than men remaining. 

Impact on Daily Activities  

Cancer related fatigue and depression significantly reduces the level of physical activity among the survivors. Those who experience fatigue were 86% more likely to reduce moderate recreational activities, such as fast walking or horticulture. Similarly, individuals with depression were 65% more likely to reduce both moderate and vigor activities. 

Underlying Factors  

Many factors contribute to the increasing vulnerability of women in these conditions:  

• Biological differences: Women can have more severe side effects than treatments such as chemotherapy and radiation due to differences in drug metabolism and immune responses. ([AACR] [1])  

• Hormonal effects: Hormonal fluctuations can affect mood and energy levels, potentially increase fatigue and depression.  

• Social roles: Women often tolerate more care responsibilities, which can increase stress and limit the time for self-care, contribute to emotional and physical exhaustion. 
 

Addressing the Disparity  

It is important to identify these gender-specific challenges to develop effective intervention. Healthcare providers should consider strategies that address the unique needs of women cancer, including  

• Personal treatment plans: Adjusting treatments to reduce side effects and manage symptoms effectively.  

• Mental Health Assistance: Providing access to counseling and support groups to address depression and emotional welfare.  

• Lifestyle intervention: encouraging physical activity and stress-stress to deal with fatigue.  

By accepting and addressing these inequalities, healthcare systems can improve overall welfare and recovery results for people survived by women cancer. 

Disclaimer:

(The views expressed are solely on the basis of research. Indiagnostic shall not be responsible for any damage caused to any person/organization directly or indirectly).